Two of A Kind – China’s First Pet Cloning Service Duplicates Star Pooch

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Surrogate mother dog and clone of Juice share enclosure at Sinogene in Beijing
A Beagle with the ID number NTR1917, who is the surrogate mother of the 24 day-old clone of Juice, shares an enclosure with its offspring at the biotech company Sinogene in Beijing, China October 11, 2018. REUTERS/Jason Lee
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By Joseph Campbell
BEIJING (Reuters) 

Juice is a one-foot tall canine wonder who has starred in dozens of Chinese film and television productions

As he gets older and his illustrious career peaks, his Beijing-based master has one wish for the mutt – to live on. Maybe forever.

A mongrel stray adopted off the streets, the nine year-old Juice — or “Guozhi” in Mandarin — is unable to reproduce since he was neutered from an early age. But his master, animal trainer He Jun, wants to continue his star pooch’s image by making a genetic clone.

 

Staff prepare a Beagle dog for surgery at a lab of the biotech company Sinogene in Beijing
Staff prepare a Beagle dog for surgery attempting to make it the surrogate mother of a clone of the dog Juice at a lab of the biotech company Sinogene in Beijing, China June 15, 2018. REUTERS/Thomas Peter

 

“Juice himself is a piece of intellectual property with social influence,” said He.

To achieve that, He went to Sinogene, China’s first biotech company to provide pet cloning services. Sinogene made headlines when it successfully cloned a gene-edited beagle in May last year. A month later, it launched commercial cloning services.

 

Staff member holds 24-day-old clone of Juice at the biotech company Sinogene in Beijing
A staff member holds 24-day-old clone of Juice at the biotech company Sinogene in Beijing, China October 11, 2018. REUTERS/Jason Lee

 

For at least 380,000 yuan (£43,719), pet owners can clone their pets.

Sinogene’s CEO Mi Jidong said the company’s pet cloning business is in its initial stages, but he plans to expand services to eventually include gene editing.

 

Twenty-four-day old clone of Juice feeds off its surrogate mother at Sinogene in Beijing
Twenty-four-day old clone of Juice feeds off its surrogate mother, a Beagle dog with the ID number NTR1917, at the biotech company Sinogene in Beijing, China October 11, 2018. REUTERS/Jason Lee

 

“We’ve discovered that more and more pet owners want their pets to accompany them for an even longer period of time,” said Mi.

China’s biotech industry is growing rapidly and, compared with similar enterprises in the West, faces relatively few regulatory barriers.

 

Owner He Jun poses with a two-month-old clone of his dog Juice in Beijing
Owner He Jun poses with a two-month-old clone of his dog Juice next to a movie poster showing source dog Juice, at his pet resort in Beijing, China November 21, 2018. REUTERS/Jason Lee

 

Earlier this year, a Shanghai lab produced the world’s first monkey clones, two long-tailed macaques. More controversially, He Jiankui of China’s Southern University of Science and Technology last month claimed he used gene-editing technology to alter the embryonic genes of twin girls.

Tin-Lap Lee, an associate professor of biomedical sciences at the Chinese University of Hong Kong, said while China has regulations on the use of animals for lab research, there are no laws explicitly covering animal cloning.

 

Sinogene staff shows a gene sample from dog Juice at He Jun's pet resort in Beijing
Sinogene staff shows a gene sample from dog Juice at He Jun’s pet resort in Beijing, China June 7, 2018. REUTERS/Damir Sagolj

 

“On the government side, the image of this cloning industry is very high-tech, and definitely…is very supportive of those high-tech industries because of their high-profit margin,” said Lee.

In Juice’s case, skin samples were collected from the dog’s lower abdomen and within weeks, Sinogene was able to isolate his DNA and fertilise an egg.

 

Veterinary doctors conduct a pregnancy test on Beagle dog NTR1917 at Sinogene in Beijing
Veterinary doctors conduct a pregnancy test on Beagle dog NTR1917, the surrogate mother of a clone of the dog Juice, at the biotech company Sinogene in Beijing, China September 10, 2018. REUTERS/Jason Lee

 

The fertilised egg is then surgically inserted into the uterus of a surrogate mother dog – in this case a beagle.

Juice’s copy, “Little Juice” — or “Zhizhi” in Chinese — was born in mid-September and stayed with its surrogate mother in Sinogene’s lab for about a month. The puppy was later given to He at a small ceremony at which the original Juice was present.

 

Sinogene staff extract a gene sample from 9 year-old Juice at He Jun's pet resort in Beijing
Sinogene staff extract a gene sample from 9 year-old Juice at He Jun’s pet resort in Beijing, China June 7, 2018. REUTERS/Damir Sagolj

 

While He has not committed Little Juice to show business just yet, he sees lots of potential.

“We believe he’ll be even better than the older Juice,” He said.

 

(Reporting by Joseph Campbell; Editing by Sam Holmes)

 

More photos ahead …

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